All functions

compute_exome_coverage()

Compute exome coverage from a region file

createOncoMatrix()

Creates matrix for oncoplot

detectMAFGenome()

A function to detect MAF genome

filterMAF()

Function to filter the mutations

filterMAF2()

Function to filter the mutations

generateBurdenPlot()

Function to generate Burden plot

generateCOSMICMutSigSimHeatmap()

Computes and plot the cosine similarity of each individual signature is computed against each COSMIC signature from COMIC V3.2

generateMutationTypePlot()

Function to generate silent and non-silent mutation plot

generateOncoPlot()

Function to generate a dashboard from a MAF file

generateOverlapPlot()

Function to generate Overlap plot

generateRibbonPlot()

Function to generate a ribbon plot depicting co-occurence and mutual exclusivity of gene mutations

generateTCGAComparePlot()

Plot the comparison of the mutation load against TCGA cohorts

generateTiTvPlot()

Function to plot the frequency of Transitions and Transversions of gene mutations

generateVariantTable()

Make variant table from maf file

getMAFDashboard()

Function to generate a dashboard from a MAF file.

getMAFdataTCGA()

Function to extract the mutation data in MAF format from TCGA

getTCGAClinicalAnnotation()

Function to extract the clinical annotations from TCGA

getTCGAClinicalColors()

Makes reasonable colors for some TCGA clinical annoations